Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T14665 |
Motixafortide
BL-8040,BKT140 (4-fluorobenzoyl),TF14016 |
CXCR | Autophagy; GPCR/G Protein; Immunology/Inflammation |
Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM). | |||
T14670 |
BMS-1166 hydrochloride
|
Others | Others |
Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM). BMS-1166 hydrochloride is an inhibitor of PD-1/PD-L1 interaction (IC50: 1.4 nM). BMS-1166 rivalries the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation. |